阿拉丁胆固醇氧化酶 来源于微生物
- 品名: 阿拉丁胆固醇氧化酶 来源于微生物
- 型号: C139686-1KU
- 产品详情
- 规格参数
基本描述
规格或纯度 | >10U/mg |
---|---|
英文名称 | Cholesterol Oxidase from microorganism |
别名 | Oxidase cholesterol;Cholesterol: oxygen oxidoreductase;Cholesterol Oxidase microbial |
英文别名 | Oxidase cholesterol;Cholesterol: oxygen oxidoreductase;Cholesterol Oxidase microbial |
单位定义 | One unit will convert 1.0 μmole of cholesterol to 4-cholesten-3-one per min at pH 7.5 at 25 °C. Note: 4-cholesten-3-one may undergo isomerization |
生化机理 | 胆固醇氧化酶及胆固醇脂酶一起用于血脂类项目如高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)以及总胆固醇(CHO)等。 |
储存温度 | -20°C储存 |
运输条件 | 超低温冰袋运输 |
产品介绍 | Cholesterol oxidase has been used in a study to improve treatment of oxysterol-mediated cytotoxicity. Cholesterol oxidase has also been used in a study that determined that cholesterol depletion impairs coupling between channel opening and vesicle release by allowing voltage-gated calcium channels to move further from release sites. Cholesterol oxidase has been used in a study to improve treatment of oxysterol-mediated cytotoxicity. Cholesterol oxidase has also been used in a study that evaluated the effects of cholesterol depletion. This study reported that cholesterol depletion impairs the coupling between channel opening and vesicle release. Additionally, cholesterol oxidase is used to determine serum cholesterol levels. The enzyme also finds application in the microanalysis of steroids in food samples. It has also been used for distinguishing 3-ketosteroids from 3β-hydroxysteroids. Transgenic plants expressing cholesterol oxidase have been investigated in the fight against the cotton boll weevil. CHOD has also been used as a molecular probe to elucidate cellular membrane structures.来自链霉菌的胆固醇氧化酶已用于评估模拟胆汁的胶束结构与酯酶活性之间的关系。来自链霉菌的胆固醇氧化酶还被用于研究鞘磷脂降解对细胞胆固醇氧化性以及细胞表面与细胞内部之间稳态分布的影响。 胆固醇氧化酶可用于检测血清胆固醇。该酶还可用于对食品样品中的类固醇进行微量分析以及用于区分3-酮类固醇与3β-羟基类固醇。目前正在研究表达胆固醇氧化酶的转基因植物对棉铃象虫甲的抵抗性。CHOD也被作为分子探针,用于阐明细胞膜结构。 Cholesterol
oxidase (CHOD) is a monomeric flavoprotein containing FAD that
catalyzes the first step in cholesterol catabolism. This Cholesterol
oxidase has been used in a study to improve treatment of
oxysterol-mediated cytotoxicity. Cholesterol oxidase has also been used
in a study that determined that cholesterol depletion impairs coupling
between channel opening and vesicle release by allowing voltage-gated
calcium channels to move further from release sites. Cholesterol oxidase
has been used in a study to improve treatment of oxysterol-mediated
cytotoxicity. Cholesterol oxidase has also been used in a study that
evaluated the effects of cholesterol depletion. This study reported that
cholesterol depletion impairs the coupling between channel opening and
vesicle release. Additionally, cholesterol oxidase is used to determine
serum cholesterol levels. The enzyme also finds application in the
microanalysis of steroids in food samples. It has also been used for
distinguishing 3-ketosteroids from 3β-hydroxysteroids. Transgenic plants
expressing cholesterol oxidase have been investigated in the fight
against the cotton boll weevil. CHOD has also been used as a molecular
probe to elucidate cellular membrane structures. |